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Secretome Sel Punca Mesenkimal sebagai Pendekatan Ilmiah Baru untuk Antiaging Kulit Akibat Paparan UV

5th January 2026 Activites, Career, News, Publication, Stem Cell 0

Menjembatani Riset Biomolekuler dan Inovasi Regeneratif melalui Dukungan Aretha Medika Utama Pendahuluan Kulit adalah garda terdepan tubuh manusia—melindungi dari lingkungan luar sekaligus mencerminkan kondisi biologis seseorang. Namun, paparan sinar matahari yang mengandung radiasi ultraviolet (UV) menjadikan kulit sebagai organ yang paling rentan mengalami penuaan dini (photoaging). Proses ini tidak hanya …

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Dr. Wahyu Widowati, M.Si

Name : Dr. Wahyu Widowati, M.Si.
Position : Head Director
Speciality : Biomedical Science

Affiliation

Medical Research Centre, Faculty of Medicine, Maranatha Christian University,
Bandung 40164, Indonesia

Academic

S1	S2	S3	S3
Universitas Brawijaya	Universitas Gadjah Mada	Universitas Padjadjaran	Fakultas Kedokteran
Toksikologi	Toksikologi	Toksikologi dan Antioksidan	Biomedik
1979-1983	1992-1994	2001-2004	2013-2016

Research

Tahun	Topik
2011	Potency of Flavonoids Increase the Differentiation of Peripheral Blood Stem Cells to Endothelial Progenitor Cells
2011	Green Tea Extract Potential to Increase Peripheral Blood Stem Cells to Endothelial Progenitor Cells
2011	Ethanolic and Water Extract of Curcuma mangga Val, Piper betle L., Catharanthus roseus [L] G.Don , Dendrophtoe petandra L. Inhibit and Prevent Breast Cancer Malignancy
2012-2013	Hypoxic and Normoxic Condition to Produce Condition Medium Mesenchymal Stem Cells from Human Umbilical Cord (HUC) as Anticancer Agent
2012-2013	Mangosteen Peel (Garcinia Mangostana) Extract Potency of Antimalarial, Antioxidant and Artemesinin Combination Therapy
2013-2014	Production of Condition Medium from Human Wharton’s Jelly Mesenchymal Stem Cells as Anticancer
2013	Development of Mangosteen Peel Extract as Antiinflammatory, Antiplatelet, Anticholesterol Inhibit cardiovascular Diseases
2014	Mangosteen Peel (Garcinia mangostana L) Extract and Xanthones as Antiadipogenesis in HepG2 Cell Line
2015-2017	Human Mesenchymal Stem Cells-Condition Medium (hMSCs-CM) Derived Wharton’s Jelly Induce Apoptosis on Cancer Stem Cells (CSCs)
2015-2017	Mangosteen Peel (Garcinia mangostana L) Extract and Xanthones as Antiinflammatory in RAW 264.7 Cells and Antidislipidemic in Athersclerotic Rat
2016-2018	Engineering human Wharton’s Jelly Mesenchymal Stem Cells (hWJMSCs) to Increase Anticancer of (hWJMSCs and Conditioned Medium (CM-WJMSCs)
2016-2018	Homing and Regenerative Potency of Wharton’s Jelly Mesenchymal Stem Cells Inhibit Osteo-Arthritis
2016-2018	Production of Conditioned Medium from Human Adipose Tissue derived Mesenchymal Stem Cells as Antiaging Candidate
2018	Isolation and Induction on Natural Killer (NK) Cells Using Interleukins for Breast Cancer Application
2018	Topical Gel from Conditioned Medium Adipose Tissue Mesenchymal Stem Cells for Diabetic Foot Ulcer (DFU) Therapy
2018	Profiling Oncology Gens, Apoptosis and Autophagy Glioma Cell Line froam Brain Cancer Patients
2018	Isolation, Characterization Breast Cancer Cells from Breast Cancer Patients

Rizal A., B.Sc., M.Biotech., M.Sc

Nama : Rizal A., B.Sc., M.Biotech., M.Sc
Jabatan : Director of Laboratory Development
Bidang Ilmu : Stem Cell Technology and Molecular Biology

Akademik

S1	S2	S2
Universitas Hasanuddin	Universitas Gadjah Mada	The University of Nottingham, UK
Biologi	Bioteknologi	Stem Cell Technology
2006-2010	2011-2014	2015-2016

Penelitian

Tahun	Topik
2010	Isolasi bakteri laut pendegradasi petroleum dan hexane
2013	Application of CHA-gelatin sheet to enhance proliferation and differentiation of umbilical cors blood stem cell from Indonesian Neonates for tissue engineering purposes
2016	Developing strategy for testing dCas9 CRISPR optogenetics for gene regulation in human embryonic stem cell

Hanna Sari Widya Kusuma, B.Sc

Name : Hanna Sari Widya Kusuma, B.Sc
Position : Director of Publication
Speciality : Biology

Academic

S1
Universitas Pendidikan Indonesia
Biologi
2010-2014

Research

Tahun	Topik
2016	Freeze Dried Berbagai Jenis Buah sebagai Antiobesitas secara in Vitro, ex Vivo dan in Vivo
2016	Aktivitas Dan Mekanisme Molekuler Antikanker Ekstrak Cosmos caudatus (Kenikir) Terhadap Kanker Servik
2016	Aktivitas Penghambatan Kerja Enzim Elastase oleh Collagen Teripang
2016	Anti-Inflammatory Potential of Gandarusa (Gendarussa vulgaris Nees) and Soursoup (Annona murica ta L) Extracts in LPS Stimulated-Macrophage Cell (RAW264.7)
2016	Antioxidant and Anti Aging Assays of Oryza sativa Extracts, Vanillin and Coumaric Acid

Rismawati Laila Qodariah, B.Pharm, Apt

Name : Rismawati Laila Qodariah, B.Pharm, Apt.
Position : Development Manager
Speciality : Pharmaceutical Science and Technology

Academic

S1	Profesi
Institut Teknologi Bandung	Institut Teknologi Bandung
Sains dan Teknologi Farmasi	Apoteker
2011-2015	2015-2016

Annisa Amalia, B.Sc

Name : Annisa Amalia, B.Sc
Position : Research Assistant
Speciality : Biochemical Analysis

Academic

S1
Universitas Padjadjaran
Biologi
2006-2010

Research

Tahun	Topik
2013	Saung Ulin Cangkurileung : Wahana Bermain dan Belajar Melalui Permainan Tradisional Sunda untuk Siswa SDN Cikeruh Kecamatan Jatinangor Sebagai Upaya Efektif Melestarikan dan Mencegah Erosi Budaya Sunda
2014	BUHILI (Bambu Hitam Lestari) untuk Angklung Alat Musik Tradisional Warisan Dunia: Kajian Pengaruh Faktor Lingkungan
2015	Emic dan Etic Angklung Sebagai Warisan Budaya Dunia
2017	Mekanisme Biomolekuler Ekstrak dan Fraksi Kunir Putih (Curcuma mangga Val.) Sebagai Antidiabet
2017	Ekstrak Daun, Ranting, dan Kulit Batang Buah Sesoot (Garcinia picorrhiza Miq) sebagai Antiobesitas secara in Vitro, ex Vivo dan in Vivo

Fajar Sukma Perdana, B.Sc

Name : Fajar Sukma Perdana, B.Sc
Position : Supply and Logistic Manager
Speciality : Biomedical Science

Academic

S1
Universitas Pendidikan Indonesia
Biologi
2014-2018

Zakiyatul Khoiriyah, B.Sc

Name : Zakiyatul Khoiriyah, B.Sc
Position : Publication Manager
Speciality : Biotechnology

Academic

S1
Universitas Jember
Biologi
2011-2016

Research

Tahun	Topik
2016	Optimization of the Immunoglobulin G (IgG) Production with a CF-10H5 Cell Line using Design of Experiments (DoE)
2015	Diversitas Genetik Vektor Dengue Aedes aegypti (L.) Berdasarkan DNA Pengkode Internal Transcribed Spacer 2 (ITS2)
2014	Biomass Support Particles (BSPS) Rhizopus oryzae menggunakan Arang Bambu : Peluang Produksi Biodiesel Dari Algal Oil Scenedesmus sp. Asal Pantai Papuma Jember

Ubaydillah Zedd Munshy, B.Sc

Name : Ubaydillah Zedd Munshy, B.Sc
Position : Research Assistant
Speciality : Molecular Biology and Microbiology

Academic

S1
Universitas Pendidikan Indonesia
Biologi
2014-2018

Research

Tahun	Topik
2018	Molecular Phylogenetic Relationship of Banana Cultivars (Musa Spp.) in Bali Based on DNA Sequences of ITS1 Region

Ni Luh Wisma Eka Yanti, B.Sc

Name : Ni Luh Wisma Eka Yanti, B.Sc
Position : Research Assistant
Speciality : Stem Cell and Molecular Biology

Academic

S1
Institut Teknologi Bandung
Bidang Ilmu Biologi
2013-2018

Research

Tahun	Topik
2017	Directed Differentiation of Human Mesenchymal Stem Cells into Chondrocytes using Micropatterning Method: Stem Cell Application Study for Cartilage Tissue Engineering

Annisa Arlisyah, B.Sc

Name : Annisa Arlisyah, B.Sc
Position : Administrator
Speciality : Biotechnology

Academic

S1
Universitas Brawijaya
Teknologi Pertanian
2011-2015

Research

Tahun	Topik
2015	Deteksi Gen Transgenik pada Produk Berbasis Kedelai dengan Metode PCR sebagai Upaya Implementasi Pelabelan PRG (Produk Rekayasa Genetika) di Indonesia
2017	Optimasi Metode Ekstraksi DNA untuk Mendeteksi Daging Babi menggunakan PCR